Treatment of visceral leishmaniasis.
نویسنده
چکیده
I agree with the authors statement, “It is an important alternative especially in patient who did not respond to conventional pentavalent antimony therapy given alone or in combination with other agents”. But they stated their experience with L-AmB treatment without trying conventional treatment. Therefore I am not in agreement with their belief that “this drug may be the first choice of treatment in VL” with a single case experience.
منابع مشابه
Visceral leishmaniasis in children
Background and Objectives: Visceral leishmaniasis is a chronic disease in Africa and Asia, children under 5 years are affecting with L.infantum and older children and young adult with L.donovani Purpose of this study describes the characteristics of epidemiologic and clinicopathophysiologic and response to treatment of patient that affected in East Azarbaijan compared with other endemic areas ...
متن کاملInterest in paromomycin for the treatment of visceral leishmaniasis (kala-azar)
Leishmaniasis is an important vector-borne disease, and it is classified as one of the most important tropical fly-borne infections. This disease can cause two types of clinical manifestations: cutaneous forms and visceral forms. Visceral leishmaniasis, which is also called kala-azar, is a very serious infection that can be fatal. The management of visceral leishmaniasis requires informed diagn...
متن کاملPLGA-based macrophage-mediated drug targeting for the treatment of visceral leishmaniasis
The potential of PLGA-nanoparticles as a carrier of amphotericin B and doxorubicin against visceral leishmaniasis was evaluated by macrophage-mediated drug targeting approach. PLGA-nanoparticles were modified by coating them with macrophage-specific ligand-lectin. Prior to in-vitro studies, characterization studies were carried out systematically include particle size, surface morphology, perce...
متن کاملEvaluation of a Novel Herbal Immunomodulator Drug (IMOD) in Treatment of Experimental Canine Visceral leishmaniasis
Toxicity and drug resistance against pentavalent antimonials, medications of choice in treatment of leishmaniasis for more than 5 decades, have become important subjects globally. This study was a randomized, open labeled trial that was designed to determine efficacy and safety of IMOD as a novel herbal immunomodulator drug for treatment of canine visceral leishmaniasis (CVL).Twenty healthy mon...
متن کاملPerceived quality of life among Visceral Leishmaniasis and HIV coinfected migrant male-workers in Northwest Ethiopia: a qualitative study
BACKGROUND There is paucity of data on quality of life as a dimension of treatment outcome among Visceral Leishmaniasis and HIV coinfected patients. This study sought to explore perceived quality of life among Visceral Leishmaniasis and HIV coinfected male migrant workers in Northwest Ethiopia. METHODS Twenty Visceral Leishmaniasis and HIV coinfected study participants took part in the in-dep...
متن کاملAn Overview of theLaboratory Diagnostic Procedures of Visceral Leishmaniasis (Kala-Azar)
Abstract Visceral leishmaniasis (Kala-azar) is a systemic infection disease that can be diagnosed by some invasive procedures such as splenic, liver biopsy or bone marrow aspiration, whichare determined as the gold standards for diagnosing of this disease. At present, a variety of noninvasive tests having different specificities and sensitivities are available for the diagnosis of visceral ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- American journal of diseases of children
دوره 146 9 شماره
صفحات -
تاریخ انتشار 1992